Ethyl 3-(dibenzylamino)-2,2-difluoropropanoate

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
2,2-Difluoro-3-(dibenzylamino)propionic acid ethyl ester
Difluorometylated Building Blocks
KUMI2F138
541547-36-8
MFCD20502283
11256065
9411735
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Boiling Point
Packaging
Storage
Ethyl 3-(dibenzylamino)-2,2-difluoropropanoate
C19H21F2NO2
333.38
≥95%
Colorless to Pale yellow Liquid

5g,10g,25g,50g,100g,200g and 500g
Store at 2-8°C temperature
Ethyl 3-(dibenzylamino)-2,2-difluoropropanoate is an important difluoromethylated building block for the preparation of various compounds of interest in organic synthesis and pharmaceuticals.
A practical synthesis of 2,2-difluoro-3-amino-propanoic acid (α,α-difluoro-β-alanine). [1]
Synthesis of Gly-ψ[(Z)CFCH]-Phe, a Fluoroalkene Dipeptide Isostere, and Its Incorporation into a Leu-enkephalin Peptidomimetic. [2]
References:
[1] A.Cheguillaume, et al, Tetrahedron Lett., 2003, 44(11), pp 2375-2377.
[2] J.F.Nadon, et al, ACS Chem. NeroSci., 2017, 8(1), pp 40-49.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H302,H315,H319,H335
P261,P305+P351+P338

NONH for all modes of Transport

1. Product Specification
2. Safety Data Sheet
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