Ethyl 3-((tert-butoxycarbonyl)amino)-2,2-difluoropropanoate

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
Ethyl 3-(Boc-amino)-2,2-difluoropropanoate
Difluorometylated Building Blocks
KUMI2F140
847986-13-4
MFCD28014563
86222896
10071910
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Boiling Point
Packaging
Storage
Ethyl 3-((tert-butoxycarbonyl)amino)-2,2-difluoropropanoate
C10H17F2NO4
253.25
≥95%
Colorless to Pale yellow Liquid

5g,10g,25g,50g,100g,200g and 500g
Store at 2-8°C temperature
Ethyl 3-((tert-butoxycarbonyl)amino)-2,2-difluoropropanoate is an important difluoromethylated building block for the preparation of various compounds of interest in organic synthesis, pharmaceuticals and radiopharmaceuticals.
Perfluorinated markers for hypoxia detection: Synthesis of sulfur-containing precursors and [18F]-labelling. [1]
Synthesis of Gly-ψ[(Z)CFCH]-Phe, a Fluoroalkene Dipeptide Isostere, and Its Incorporation into a Leu-enkephalin Peptidomimetic. [2]
References:
[1] T.Fujimoto, et al, Bioorg. Med. Chem. Lett., 2011, 21(21), pp 6409-6417.
[2] J.F.Nadon, et al, ACS Chem. NeuroSci., 2017, 8(1), pp 40-49.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H302,H315,H319,H335
P261,P305+P351+P338

NONH for all modes of Transport

1. Product Specification
2. Safety Data Sheet
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