Tert-butyl 3,3-difluorocyclobutylcarbamate

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
N-(3,3-difluorocyclobutyl)carbamic acid tert-butyl ester
Difluoromethylating Building Blocks
KUMI2F78
1029720-19-1
MFCD10001483
71288132
23741899
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
Tert-butyl 3,3-difluorocyclobutylcarbamate
C9H15F2NO2
207.22
≥96.0%
White to Pale yellow Solid

5g,10g,25g,50g,100g,200g and 500g
Store at room temperature
Tert-butyl 3,3-difluorocyclobutylcarbamate is a useful difluorocyclobutane building block for the synthesis of various pharmaceutical active moleculars, such as HCV NS4B inhibitors and Pan-JNK inhibitors, etc..
Discovery of novel HCV inhibitors: synthesis and biological activity of 6-(indol-2-yl)pyridine-3-sulfonamides targeting hepatitis C virus NS4B. [1]
Lead Optimization toward Proof-of-Concept Tools for Huntington's Disease within a 4-(1 H -Pyrazol-4-yl)pyrimidine Class of Pan-JNK Inhibitors. [2]
References:
[1] X.Zhang, et al, Bioorg. Med. Chem. Lett., 2013, 23(13), pp 3947-3953.
[2] J.Wityak, et al, J. Med. Chem., 2015, 58(7), pp 2967-2987.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319,H335
P280,P305+P351+P338

NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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