Zinc difluoromethanesulfinate

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem SID
Reaxys RN
Baran difluoromethylation reagent,Bis(((difluoromethyl)sulfinyl)oxy)zinc,DFMS
Difluoromethylating Reagents
KUMI4F01
1355729-38-2
MFCD23134675
329767342
22257547
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
Zinc difluoromethanesulfinate
C2H2F4O4S2Zn
295.55
≥95%
White to Beige Solid
60-70ºC
1g,5g,10g and 50g
Store 2-8ºC (recommended)
Zinc difluoromethanesulfinate (DFMS) is part of a zinc sulfinate toolbox developed by Phil Baran for the simple and rapid diversification of heterocycles.
DFMS is a new reagent for direct difluoromethylation of organic substrates via a radical process. This mild, operationally simple, chemoselective, and scalable difluoromethylation method is compatible with a range of nitrogen-containing heteroarene substrates of varying complexity as well as select classes of conjugated p−systems and thiols.
Practical and innate carbon–hydrogen functionalization of heterocycles.[1]
A New Reagent for Direct Difluoromethylation.[2]
References:
[1] Y.Fujiwara,J.A.Dixon,F.O'Hara,E.D.Funder,D.D.Dixon,R.A.Rodrigue,R.D.Baxter,B.Herlé,N.Sach,M.R.Collins,Y.Ishihara,P.S.Baran, Nature,2012,492,pp 95-99.
[2] Y.Fujiwara, J.A.Dixon, R.A. Rodrigne, R.D.Baxter,D.D.Dixon,M.R.Collins, D.G.Blackmond,P.S.Baran, J.Am.Chem.Soc.,2012,134(3),pp 1494-1497.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319,H335
P261,P305+P351+P338
2931.90.9010
NONH for all modes of transport

Please inquire for pricing and availability of this product by writing email to sales@kumidas.com.