1-Bromo-4-fluoro-2-isopropoxybenzene

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
1-bromo-4-fluoro-2-propan-2-yloxybenzene
Fluorinated Building Blocks
KUMI1F165
610797-49-4
MFCD10699697
46738825
9758575
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Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Boiling Point
Packaging
Storage
1-Bromo-4-fluoro-2-isopropoxybenzene
C9H10BrFO
233.08
97%
Colorless Liquid

5g,10g,20g,50g,100g,200g and 500g
Store at room temperature
1-Bromo-4-fluoro-2-isopropoxybenzene is a useful fluorinated building block for the synthesis of various pharmaceutically active substances, such as α1a/1d-selective adrenergic receptor antagonists and selective estrogen receptor modulators.
(Phenylpiperidinyl)cyclohexylsulfonamides: Development of α1a/1d-selective adrenergic receptor antagonists for the treatment of benign prostatic hyperplasia/lower urinary tract symptoms (BPH/LUTS). [1]
Regioselectivity of fluorine substitution by alkoxides on unsymmetrical difluoroarenes​. [2]
Regioselective SNAr reactions of substituted difluorobenzene derivatives: practical synthesis of fluoroaryl ethers and substituted resorcinols. [3]
Analogues of Fenarimol Are Potent Inhibitors of Trypanosoma cruzi and Are Efficacious in a Murine Model of Chagas Disease. [4]
References:
[1] G.Chiu, et al, Bioorg. Med. Chem. Lett., 2007, 17(14), pp 3930-3934.
[2] R.Dirr, et al, Tetrahedron Lett., 2008, 49(31), pp 4588-4590.
[3] S.G.Ouellet, et al, Tetrahedron Lett., 2009, 50(27), pp 3776-3779.
[4] M.Keenan, et al, J. Med. Chem., 2012, 55(9), pp 4189-4204.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H302
P301+P312+P330
2942000090
NONH for all modes of transport.

1. Product Specification
2. Safety Data Sheet
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