(1S,2S)-2-Fluorocyclopropane-1-carboxylic acid

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
cis-2-Fluoro-cyclopropanecarboxylic acid
Fluorinated Building Blocks
KUMI1F175
127199-14-8
MFCD19237459
9793716

Reaxys ID
7165425
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Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
(1S,2S)-2-Fluorocyclopropane-1-carboxylic acid
C4H5FO2
104.08
95%
White Solid
55-56°C
5g,10g,20g,50g,100g,200g and 500g
Store at room temperature
(1S,2S)-2-Fluorocyclopropane-1-carboxylic acid is a chiral fluorocyclopropyl building block for the synthesis of various pharmaceutical active substances, such as TYK2 inhibitors and C-KIT kinase inhibitors.
Lead optimization of a 4-aminopyridine benzamide scaffold to identify potent, selective, and orally bioavailable TYK2 inhibitors. [1]
Identification and pharmacological characterization of 3,6-diazabicyclo[3. 1.1]heptane-3-carboxamides as novel ligands for the α4β2 and α6/α3β2β3 nicotinic acetylcholine receptors (nAChRs). [2]
References:
[1] J.Liang, et al, J. Med. Chem., 2013, 56(11), pp 4521-4536.
[2] J.P.Strachem. et al, Eur. J. Med. Chem., 2014, 86, pp 60-74.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319,H335
P271,P261,P280
2915907090
NONH for all modes of transport.

1. Product Specification
2. Safety Data Sheet
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