(1S,2S)-2-Fluorocyclopropane-1-carboxylic acidis a chiral fluorocyclopropyl building block for the synthesis of various pharmaceutical active substances, such as TYK2 inhibitors and C-KIT kinase inhibitors.
Lead optimization of a 4-aminopyridine benzamide scaffold to identify potent, selective, and orally bioavailable TYK2 inhibitors.
Identification and pharmacological characterization of 3,6-diazabicyclo[3. 1.1]heptane-3-carboxamides as novel ligands for the α4β2 and α6/α3β2β3 nicotinic acetylcholine receptors (nAChRs).
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NONH for all modes of transport.
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