2,4-Difluorophenylacetonitrileis a fluorinated building block for the synthesis of various pharmaceutial compounds. Such as HIV-1 reverse transcriptase inhibitors, indoleamine-2,3-dioxygenase 1 inhibitors, etc..
Synthesis of novel inhibitors of the HIV-1 protease: difunctional enols of simple N-protected amino acids. 
Synthesis and biological evaluation of new conformationally restricted S-DABO hybrids as non-nucleoside inhibitors of HIV-1 reverse transcriptase. 
Nitrobenzofurazan derivatives of N'-hydroxyamidines as potent inhibitors of indoleamine-2,3-dioxygenase 1.