2,4-Difluorophenylacetonitrile

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
2,4-Difluorobenzyl Cyanide
Fluorinated Building Blocks
KUMI2F117
656-35-9
MFCD00009971
69565
2614808
Chemical Name
Molecular Formula
Molecular Weight
Assay(Analysis Method)
Appearance
Boiling Point
Packaging
Storage
2,4-Difluorophenylacetonitrile
C8H5F2N
153.13
≥98%
Colorless Liquid
98°C/10 mmHg
5g,10g,50g,100g,200g and 500g
Store at 2-8°C temperature
2,4-Difluorophenylacetonitrile is a fluorinated building block for the synthesis of various pharmaceutial compounds. Such as HIV-1 reverse transcriptase inhibitors, indoleamine-2,3-dioxygenase 1 inhibitors, etc..
Synthesis of novel inhibitors of the HIV-1 protease: difunctional enols of simple N-protected amino acids. [1]
Synthesis and biological evaluation of new conformationally restricted S-DABO hybrids as non-nucleoside inhibitors of HIV-1 reverse transcriptase. [2]
Nitrobenzofurazan derivatives of N'-hydroxyamidines as potent inhibitors of indoleamine-2,3-dioxygenase 1. [3]
References:
[1] M.Vaillancourt, et al, Bioorg. Med. Chem., 1994, 2(5), pp 343-355.
[2] H.Wu, et al, MedChemComm., 2014, 4, pp 468-473.
[3] S.Paul, et al, Eur. J. Med. Chem., 2016, 121, pp 364-375.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H302+H312+H332,315,H319,H335
P261,P280,P305+P351+P338
2926907090
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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