2-bromo-5-fluoro-3-nitropyridine is a useful building block for the synthesis of various substituted pyridine compounds.
Inhibitors of human immunodeficiency virus type 1 (HIV-1) attachment. 12. Structure-activity relationships associated with 4-fluoro-6-azaindole derivatives leading to the identification of 1-(4-benzoylpiperazin-1-yl)-2-(4-fluoro-7-[1,2,3]triazol-1-yl-1h-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione (BMS-585248). 
 A.Regueiro-Ren, et al, J. Med. Chem., 2013, 56(4), pp 1656-1669.