2-Fluoro-3-pyridinecarboxylic acid (also named as 2-Fluoronicotinic acid) is a building block for the synthesis of various pharmaceuticals substances, such as HCV NS5B polymerase inhibitors, BRAFV600E inhibitors, Human Reticulocyte 15-Lipoxygenase-1 inhibitors and [18F]N-(2-(diethylamino)ethyl)-6-fluoronicotinamide used as a PET melanoma imaging radiotracer.
Oxadiazole derivatives as a novel class of antimitotic agents: Synthesis, inhibition of tubulin polymerization, and activity in tumor cell lines. 
Discovery of [18F]N-(2-(diethylamino)ethyl)-6-fluoronicotinamide: a melanoma positron emission tomography imaging radiotracer with high tumor to body contrast ratio and rapid renal clearance. 
Discovery of Potent and Selective Inhibitors of Human Reticulocyte 15-Lipoxygenase-1. 
Pyridine carboxamides: Potent palm site inhibitors of HCV NS5B polymerase. 
Design, synthesis and biological evaluation of novel 5-phenyl-1H-pyrazole derivatives as potential BRAFV600E inhibitors.