2-Fluorocyclopropane-1-carboxylic acid

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
2-Fluorocyclopropane-carboxylic acid
Fluorinated Building Blocks
KUMI1F176
156816-78-3
MFCD21604147

PubChem ID
10125050

Reaxys ID

Reaxys ID
6591719  
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Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
2-Fluorocyclopropane-1-carboxylic acid
C4H5FO2
104.08
95%
White Solid
55-56°C
5g,10g,20g,50g,100g,200g and 500g
Store at room temperature
2-Fluorocyclopropane-1-carboxylic acid is a racemic fluorocyclopropyl building block for the synthesis of various pharmaceutical active substances, e.g. the corresponding racemic ethylester and its anologues were used as starting materials for the synthesis of carboxamides, of the cis- and trans-isomers of analogues of tranylcypromine, an anti-depressive drug and several of its homologous fluorinated cyclopropylmethyl and cyclopropylethyl amines. 
Fluorocyclopropyl quinolones. 1. Synthesis and structure-activity relationships of 1-(2-fluorocyclopropyl)-3-pyridonecarboxylic acid antibacterial agents. [1]
Sythesis, reactions and structural features of monofluorinated cyclopropanecarboxylates. [2]
References:
[1] S.Atarashi, et al, J. Med. Chem., 1993, 26(22), pp 3444-3448.
[2] G.Haufe, et al, J. F. Chem., 2002, 114(2), pp 189-198.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319,H335
P271,P261,P280
2915907090
NONH for all modes of transport.

1. Product Specification
2. Safety Data Sheet
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