(2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol is a pharmaceutically useful fluorinated building block in the synthesis of triazole and imidazole type compounds used as antifungal therapeutic agents, typically for the end preparation of Efinaconzaole.
Optically active antifungal azoles. I. Synthesis and antifungal activity of (2R,3R)-2-(2,4-difluorophenyl)-3-mercapto-1-(1H-1,2,4-triazol-1-yl)-2-b utanol and its stereoisomers.
Discovery of novel indazole-linked triazoles as antifungal agents. 
The Process Development of Ravuconazole: An Efficient Multikilogram Scale Preparation of an Antifungal Agent. 
Synthesis and Activity of Novel Indole Linked Triazole Derivatives as Antifungal Agents. 
An enantioselective synthesis of the key intermediate for triazole antifungal agents; Application to the catalytic asymmetric synthesis of efinaconazole.