3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl bromide is a pharmaceutically useful fluorinated building block in the synthesis of sodium-dependent glucose transporter (SGLT) inhibitors, typically used as Canagliflozin intermediate II.
Discovery of canagliflozin, a novel C-glucoside with thiophene ring, as sodium-dependent glucose cotransporter 2 inhibitor for the treatment of type 2 diabetes mellitus (1).
β-Selective C-Arylation of Diisobutylaluminum Hydride Modified 1,6-Anhydroglucose: Synthesis of Canagliflozin without Recourse to Conventional Protecting Groups. 
Copper-Catalyzed Arylation of Benzylic C–H bonds with Alkylarenes as the Limiting Reagents. 
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 W.Zhang, et al, J. Am. Chem. Soc., 2017, 139(23), pp 7709-7712.