3-bromo-5-fluorophenylboronic acid

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
(3-bromanyl-5-fluoranyl-phenyl)boronic acid
Fluorinated Building Blocks
KUMI1F66
849062-37-9
MFCD06411356
16217688
18349581
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
3-bromo-5-fluorophenylboronic acid
C6H5BBrFO2
218.82
≥96%
White to Yellow Solid
>300°C
10g,25g,50g,100g,500g and 1kg
Store at room temperature
3-bromo-5-fluorophenylboronic acid is a useful fluorinated building block in the synthesis of various pharmaceutical and API compounds, such as inhibitors of fatty acid amide hydrolase and prolyl hydroxylase inhibitors.
Functionalization of dihalophenylboronic acids by deprotonation of their N-butyldiethanolamine esters. [1]
3-(Benzo[d][1,3]dioxol-5-ylamino)-N-(4-fluorophenyl)thiophene-2-carboxamide overcomes cancer chemoresistance via inhibition of angiogenesis and P-glycoprotein efflux pump activity. [2]
References:
[1] K.Durka, et al, Eur. J. Org. Chem., 2009, 25, pp 4325-4332.
[2] R.Mudududdla, et al, Org. Biomol. Chem., 2015, 13(4), pp 4296-4309.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319,H335
P261,P304+P340,P305+P351+P338,P405
2931900090
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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