3-chloro-2,4-difluorobenzoic acid

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
2,4-difluoro-3-chlorobenzoic acid
Fluorinated Building Blocks
KUMI2F116
154257-75-7
MFCD01631387
2773532
7290655
Chemical Name
Molecular Formula
Molecular Weight
Assay(Analysis Method)
Appearance
Melting Point
Packaging
Storage
3-chloro-2,4-difluorobenzoic acid
C7H3ClF2O2
192.55
≥98%
White to Yellow Solid
174-175°C
5g,10g,50g,100g,200g and 500g
Store at 2-8°C temperature
3-chloro-2,4-difluorobenzoic acid is a halogenated building blocks for the synthesis of various pharmaceutial compounds. Such as 2,4-Difluoro-3,5-dichlorobenzoic acid as a key intermediate for preparing quinolone-3-carboxylic acids.
Discovery of Novel DNA Gyrase Inhibiting Spiropyrimidinetriones: Benzisoxazole Fusion with N-Linked Oxazolidinone Substituents Leading to a Clinical Candidate (ETX0914). [1]
An efficient synthesis of 2,4-difluoro-3,5-dichlorobenzoic acid. [2]
References:
[1] G.S.Basarab, et al, J. Med. Chem., 2015, 58(5), pp 6264-6282.
[2] W.Zhou, et al, J. Chem. Res., 2015, 39(5), pp 277-278.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319,H335
P271,P261,P280
2916399090
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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