3-Fluoro-4-pyridinecarboxylic acid 

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
3-Fluoroisonicotinic acid
Fluorinated Building Blocks
KUMI1F157
393-53-3
MFCD03789251

Reax
345361

Reax
383678
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
3-Fluoro-4-pyridinecarboxylic acid  
C6H4FNO2
141.10
98%
White to Off-white Solid
251-254°C
5g,10g,20g,50g,100g,200g and 500g
Store at room temperature
3-Fluoro-4-pyridinecarboxylic acid (also named as 3-Fluoroisonicotinic acid) is a fluorinated building block for the synthesis of various pharmaceuticals substances, such as HIV-1 reverse transcriptase, histone demethylase inhibitors, NFAT transcription factor regulator, etc..
3,5-Bis(trifluoromethyl)pyrazoles: A novel class of NFAT transcription factor regulator. [1]
Design of annulated pyrazoles as inhibitors of HIV-1 reverse transcriptase. [2]
Identification of selective and potent inhibitors of fibroblast activation protein and prolyl oligopeptidase. [3]
Synthesis, structure-activity relationships, and anticonvulsant activities of 2-amino-4H-pyrido[3,2-e][1,3]thiazin-4-one derivatives as orally active AMPA receptor antagonists. [4]
Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-pyridine Carboxylate Derivatives. [5]
References:
[1] S.W.Djuric, et al, J. Med. Chem., 2000, 43(16), pp 2975-2981.
[2] Z.K.Sweeney, et al, J. Med. Chem., 2008, 51(23), pp 7449-7458.
[3] S.E.Poplawski, et al, J. Med. Chem., 2013, 56(9), pp 3467-3477.
[4] H.Inami, et al, Bioorg. Med. Chem., 2015, 23(8), pp 1788-1799.
[5] S.M.Westaway, et al, J. Med. Chem., 2016, 59(4), pp 1357-1369.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319,H335
P261,P305+P351+P338
2933399990
NONH for all modes of transport.

1. Product Specification
2. Safety Data Sheet
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