3-fuoro-2-nitropyridine

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
2-nitro-3-fluoropyridine, 3-fluoranyl-2-nitro-pyridine
Fluorinated Building Blocks
KUMI1F115
54231-35-5
MFCD04114127
2762802
1637068
Chemical Name
Molecular Formula
Molecular Weight
Assay(Analysis Method)
Appearance
Melting Point
Packaging
Storage
3-fuoro-2-nitropyridine
C5H3FN2O2
142.09
≥98%
Light Yellow Solid
38-39°C
5g,10g,25g,50g,100g,200g,500g and 1kg
Store at 2-8°C temperature
3-fuoro-2-nitropyridine is a useful fluorinated building block for the synthesis of various pharmaceutical compounds, such as PDE10A inhibitors.
Discovery of selective biaryl ethers as PDE10A inhibitors: improvement in potency and mitigation of Pgp-mediated efflux. [1]
Synthesis of 3-substituted 2-aminopyridines via displacement of 3-fluoro-2-nitropyridine. [2]
Diversity-Oriented Synthesis as a Strategy for Fragment Evolution against GSK3β. [3]
References:
[1] R.M. Rzasa, et al, Bioorg. Med. Chem. Lett., 2012, 22(24), pp 7371-7375.
[2] J.Culshaw, et al, Synlett., 2012, 23(12), pp 1816-1820.
[3] Y.Wang, et al, ACS Med. Chem. Lett., 2016, 7(9), pp 852-856.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319,H335
P261,P271,P280
2933399990
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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