4-(3-chloro-4-fluoro-phenylamino)-7-phenylsulphonyl-6-nitro-quinazoline

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem SID
Reaxys RN
N-(3-Chloro-4-fluorophenyl)-6-nitro-7-(phenylsulfonyl)quinazolin-4-amine
Fluorinated Building Blocks
KUMI1F37
945553-94-6
MFCD17018718
329765803
15522375
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Chemical Name
Molecular Formula
Molecular Weight
Assay(Analysis Method)
Appearance
Melting Point
Packaging
Storage
4-(3-chloro-4-fluoro-phenylamino)-7-phenylsulphonyl-6-nitro-quinazoline
C20H12ClFN4O4S
458.86
≥97.0%(HPLC)
Solid
284-286°C
250mg,500mg,1g,2g,5g and 10g
Store at room temperature
4-(3-chloro-4-fluoro-phenylamino)-7-phenylsulphonyl-6-nitro-quinazoline is a useful and potential pharmaceutical intermediate for preparation of the novel 4-anilinoquinzaolines which act as inhibitors of epidermal growth factor receptor.
Design, synthesis and biological evaluation of novel 4-anilinoquinazolines with C-6 urea-linked side chains as inhibitors of the epidermal growth factor receptor. [1]
Reference:
[1] X.Zhang, T.Peng, X.Ji, J.Li, L.Tong, Z.Li, W.Yang, Y.Xu, M.Li, J.Ding, H.Jiang, H.Xie,H. Liu, Bioorg. Med. Chem., 2013, 21(24), pp 7988-7998.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H302,H315,H319,H335
P261,P280,P305+P351+338

NONH for all modes of transport

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