4-Fluoro-2-methylphenol

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem SID
Reaxys RN
5-Fluoro-2-hydroxytoluene, 4-Fluoro-O-cresol, 4FOC
Fluorinated Building Blocks
KUMI1F108
452-72-2
MFCD00075088
24860459
2041490
Chemical Name
Molecular Formula
Molecular Weight
Assay(Analysis Method)
Appearance
Melting Point
Packaging
Storage
4-Fluoro-2-methylphenol
C7H7FO
126.13
≥98%
White to Yellow Solid
37-38°C
5g,10g,50g,100g,200g and 500g
Store at 2-8°C temperature
4-Fluoro-2-methylphenol (also named as 4-Fluoro-O-cresol, 4FOC) is a fluorinated aromatic building block typically used to synthesize antagonists of Ghrelin, an acylated peptide that stimulates the release of growth hormone from the pituitary.
Ghrelin and des-acyl ghrelin: two major forms of rat ghrelin peptide in gastrointestinal tissue. [1]
A role for ghrelin in the central regulation of feeding. [2]
Discovery of a new class of ghrelin receptor antagonists. [3]
 References:
[1] H.Hosoda, et al, Biochem. Biophys. Res. Commun., 2000, 279(3), pp 909-913.
[2] M.Nakazato, et al, Nature, 2001, 409(6817), pp 194-198.
[3] J.T.Mihalic, et al, Bioorg. med. Chem. Lett., 2012, 22(5), pp 2046-2051. 
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
315,H319,H335
P261,P305+P351+P338
2908193500
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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