5-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)furan-2-carbaldehyde is an imtermediate in the synthesis of Lapatinib,which is a dual tyrosine kinase inhibitor which interrupts the HER2/neu and epidermal growth factor receptor (EGFR) pathwaysan and therefore is used as an orally active drug for breast cancer and other solid tumours.
1,2-Diarylpyrroles as potent and selective inhibitors of cyclooxygenase-2. 
Biochemical and clinical implications of the ErbB/HER signaling network of growth factor receptors. 
Epidermal growth factor receptor inhibitors: a new prospective in the treatment of lung cancer. 
A unique structure for epidermal growth factor receptor bound to GW572016 (Lapatinib): relationships among protein conformation, inhibitor off-rate, and receptor activity in tumor cells.
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