5-Fluoropyridine-3-carbonitrile (also named as 5-Fluoronicotinonitrile, 3-Cyano-5-fluoropyridine) is a fluorinated building block for the synthesis of various pharmaceuticals substances, such as Triazolopyridyl compounds as Aldosterone Synthase Inhibitors, Nicotinamide Phosphoribosyltransferase (NAMPT) and Histone Deacetylase (HDAC) Dual Inhibitors.
Pd-catalyzed nucleophilic fluorination of aryl bromides. 
Small Molecule Inhibitors Simultaneously Targeting Cancer Metabolism and Epigenetics: Discovery of Novel Nicotinamide Phosphoribosyltransferase (NAMPT) and Histone Deacetylase (HDAC) Dual Inhibitors. 
 H.G.Lee, et al, J. Am. Chem. Soc., 2014, 136(10), pp 3792-3795.
 G.Dong, et al, J. Med. Chem., 2017, 60(19), pp 7965-7983.
UN 3439 6.1/PG III
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