5-Fluoropyridine-3-carbonitrile

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
5-Fluoronicotinonitrile, 3-Cyano-5-fluoropyridine
Fluorinated Building Blocks
KUMI1F197
696-42-4
MFCD09027295

Reax
22463471

Reax
471853
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
5-Fluoropyridine-3-carbonitrile
C6H3FN2
122.10
98%
White to Beige Solid
54-55°C
5g,10g,25g,50g,100g,250g and 500g
Store at room temperature
5-Fluoropyridine-3-carbonitrile (also named as 5-Fluoronicotinonitrile, 3-Cyano-5-fluoropyridine) is a fluorinated building block for the synthesis of various pharmaceuticals substances, such as Triazolopyridyl compounds as Aldosterone Synthase InhibitorsNicotinamide Phosphoribosyltransferase (NAMPT) and Histone Deacetylase (HDAC) Dual Inhibitors.
Pd-catalyzed nucleophilic fluorination of aryl bromides. [1]
Small Molecule Inhibitors Simultaneously Targeting Cancer Metabolism and Epigenetics: Discovery of Novel Nicotinamide Phosphoribosyltransferase (NAMPT) and Histone Deacetylase (HDAC) Dual Inhibitors. [2]
References:
[1] H.G.Lee, et al, J. Am. Chem. Soc., 2014, 136(10), pp 3792-3795.
[2] G.Dong, et al, J. Med. Chem., 2017, 60(19), pp 7965-7983.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Danger
H302,H318,H400
P273,P280,P305+P351+P338
2933399990
UN 3439 6.1/PG III

1. Product Specification
2. Safety Data Sheet
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