6-fluoro-3-hydroxypyrazine-2-carboxylic acid

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
5-fluoro-2-oxo-1H-pyrazine-3-carboxylic acid
Fluorinated Building Blocks
KUMI1F67
1079990-21-8
 
122129615

image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
6-fluoro-3-hydroxypyrazine-2-carboxylic acid
C5H3FN2O3
158.09
≥97%(HPLC)
Yellow Solid

5g,10g,25g,50g,100g,500g and 1kg
Store at room temperature
6-fluoro-3-hydroxypyrazine-2-carboxylic acid is a useful fluorinated building block and pharmaceutical intermediate in the synthesis of 6-fluoro-3- hydroxypyrazine-2-carboxamide commercially named favipiravir, which is a unique viral RNA Polymerase inhibitor for the treatment of Influenza, acting on viral genetic copying to prevent its reproduction.
Synthesis and crystal structure of 6-fluoro-3-hydroxypyrazine-2-carboxamide. [1]
A practical and step-economic route to Favipiravir. [2]
References:
[1] F.Shi, et al, Drug Discov. Ther., 2014, 8(3), pp 117-120.
[2] F.Lin, et al, Chem. Pap., 2017, 71(11), pp 2153-2158.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H302,H315,H319,H335
P261,P305+P351+P338
28459090
NONH for all modes of transport
Sales restrictions may apply.
1. Product Specification
2. Safety Data Sheet
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