Methyl 4-fluoro-1H-pyrrole-2-carboxylate is a useful building block for the synthesis of various fluorinated pharmaceutically active molecules, such as Pyrrolopyridazine JAK3 Inhibitors for the treatment of inflammatory and autoimmune diseases, Pyrrole derivatives as positive allosteric modulators of metabotropis receptors.
Synthesis and characterization of partially β-fluorinated 5,10,15,20-tetraphenylporphyrins and some derivatives. 
Optimization of Novel Indole-2-carboxamide Inhibitors of Neurotropic Alphavirus Replication. 
 J.Leroy, et al, Tetrahedron, 2002, 58(33), pp 6713-6722.
 J.A.Sindac. et al , J. Med. Chem., 2013, 56(22), pp 9222-9241.