PyFluor

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem SID
Reaxys RN
2-Pyridinesulfonyl Fluoride,Pyridine-2-sulfonyl Fluoride
Fluorinating Reagents, [18]F-Labelled Precursors
KUMI1F01
878376-35-3
MFCD09265513
11615218
10151877
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
PyFluor
C5H4FNO2S
161.15
98%
White to Slightly pale yellow Solid
29-34°C
5g,10g,25g,50g,100g,250g and 500g
Stored 2-8°C 
PyFluor can be utilized for the deoxyfluorination of primary and secondary alcohols in combination with an amidine or guanidine base. Compared other common deoxyfluorination reagents(e.g.DAST) exhibits less elimination side products in direct comparison on certain substrates.  This newly-developed reagent is also employed as [18F]-labeled precursor for no-carrier-added deoxy-radiofluorination.
A convenient preparation of heteroaryl sulfonamides and sulfonyl fluorides from heteroaryl thiols. [1]
PyFluor: A Low-Cost, Stable, and Selective Deoxyfluorination Reagent. [2]
References:
[1] S.W.Wright, et al, J. Org. Chem., 2006, 7(13), pp 1080-1084.
[2] A.G. Doyle, et al, J. Am. Chem. Soc., 2015, 137 (30), pp 9571–9574.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Danger
H314
P280,P303+P361+P353,P304+P340+P310,P305+P351+P338
2933399990
UN 3261 8/PG II

1. Product Specification
2. Safety Data Sheet
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