N-Fluoro-N'-(chloromethyl)triethylenediamine Bis(tetrafluoroborate)

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem SID
Reaxys RN
Selectfluor, F-TEDA-BF4
Fluorinating Reagents, [18]F-Labeled Precursors
KUMI9F01
140681-55-6
MFCD00142607
24867509
5368649
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay(Analysis Method)
Appearance
Melting Point
Packaging
Storage
1-Chloromethyl-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate)
C7H14B2ClF9N2
354.26
≥98.0% (Indirect iodimetry, Active Fluorine Content ≥5.25%)
White to Off-white Powder
260°C(lit.)
5g,10g,20g,50g,100g,250g,500g,1kg,5kg and 25kg
Store at room temperature
N-Chloromethyl-N′-fluorotriethylenediammonium bis(tetrafluoroborate) (also named as SelectFluor, F-TEDA-BF4) is a safe, nontoxic and easy to handle electrophilic N-F type fluorinating reagent, typically used for greener fluorination of acetoacetamides in PEG-400. This reagent rapidly fluorinates a wide range of organic molecules under mild conditions with high efficiency and selectivity.
Regioselective Fluorohydroxylation Reaction of Arylallenes. [1]
Regiospecific fluorination of functionalized phenols. [2]
Catalyst-free and highly selective electrophic mono-fluorination of acetoacetamides in PEG-400. [3]
Metal-Free Fluorination of C(sp3)-H Bonds using a Catalytic N-Oxyl Radical. [4]
Solvent‐Free Fluorination of Electron‐Rich Aromatic Compounds with F‐TEDA‐BF4: Toward “Dry” Processes. [5]
Fluorination‐Oxidation of 2‐Hydroxymethylindole Using Selectfluor. [6]
References:
[1] C.Zhou, et al ,Org. Lett. 2008, 10(4), pp 581-583.
[2] T.Furuya, et al, J. Am. Chem. Soc., 2009, 13(5), pp 1662-1663.
[3] G.Zhang, et al, Green Chem., 2012, 4(14), pp 1159-1162.
[4] Y.Amaoka, et al, M. Inoue, Org. Lett., 2013, 15(9), pp 2160-2163.
[5] P.A.Zaikin, et al, Eur. J. Org. Chem., 2017, 17, pp 2469-2474.
[6] X.Jiang, et al, Adv. Synth. Catal., 2017, 359(15), pp 853-858.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Danger
H252,H302,H317,H318,H412
P235+P410,P273,P280,P305+P351+P338
2933599565
UN 3088 4.2/PG II
Selectfluor is a registered trademark of Air Products and Chemicals, Inc.
1. Product Description
2. Safety Data Sheet
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