(trans)-2-fluorocyclopropanecarboxylic acid

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
(1S,2R)-2-fluorocyclopropane-1-carboxylic acid
Fluorinated Building Blocks
KUMI1F193
130340-04-4
MFCD11499062

PubChem ID

PubChem ID
10103129

Reaxys ID

Reaxys ID
3601765  
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Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
(trans)-2-fluorocyclopropanecarboxylic acid
C4H5FO2
104.08
98%
White Solid
41-42°C
5g,10g,20g,50g,100g,200g and 500g
Store at room temperature
(trans)-2-fluorocyclopropanecarboxylic acid is a chiral monofluorinated fluorocyclopropyl building block for the synthesis of various pharmaceutical active substances, e.g. C-KIT kinase inhibitors.
Fluorocyclopropyl quinolones. 1. Synthesis and structure-activity relationships of 1-(2-fluorocyclopropyl)-3-pyridonecarboxylic acid antibacterial agents. [1]
Lead optimization of a 4-aminopyridine benzamide scaffold to identify potent, selective, and orally bioavailable TYK2 inhibitors. [2]
References:
[1] S.Atarashi, et al, J. Med. Chem., 1993, 26(22), pp 3444-3448.
[2] J.Liang, et al, J. Med. Chem., 2013, 56(11), pp 4521-4536.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319,H335
P271,P261,P280
2915907090
NONH for all modes of transport.

1. Product Specification
2. Safety Data Sheet
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