Ethyl 2-(5-bromopyridin-2-yl)-2,2-difluoroacetate

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
5-bromopyridine-α,α-difluoro-2-acetic acid ethyl ester
Difluoromethylated Building Blocks
KUMI2F246
294181-95-6
MFCD12404043
10779083
8764951
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Boiling Point
Packaging
Storage
Ethyl 2-(5-bromopyridin-2-yl)-2,2-difluoroacetate
C9H8BrF2NO2
280.07
≥98%
Colorless to Yellow Liquid

5g,10g,25g,50g,100g,200g and 500g
Store at 2-8°C temperature
Ethyl 2-(5-bromopyridin-2-yl)-2,2-difluoroacetate is a difluorinated building block that typically used in the preparation of Oteseconazole (VT-1161) as a tetrazole antifungal agent potentially for the treatment of candidal vaginal infection.
Design and optimization of highly-selective fungal CYP51 inhibitors. [1]
VT-1161 Protects Immunosuppressed Mice from Rhizopus arrhizus var. arrhizus Infection. [2]
References:
[1] W.J.Hoekstra, et al, Bioorg. Med. Chem. Lett., 2014, 24(15), pp 3455-3458.
[2] T.Gebremariam, et al, Antimicrob. Agents Chemother., 2015, 59(12), pp 7815-7817.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Not classified as a hazardous substance or mixture


2933299090
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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