Ethyl 2-(5-bromopyridin-2-yl)-2,2-difluoroacetate is a difluorinated building block that typically used in the preparation of Oteseconazole (VT-1161) as a tetrazole antifungal agent potentially for the treatment of candidal vaginal infection.
Design and optimization of highly-selective fungal CYP51 inhibitors. [1]
VT-1161 Protects Immunosuppressed Mice from Rhizopus arrhizus var. arrhizus Infection. [2]
-2,2-difluoroacetate-45c48.png)