(Me4N)SCF3 is a versatile,beach-stable,operationally simple and highly selective reagent for various late-stage synthetic applications, such as one-pot synthesis of trifluoromethylated amines and acyl fluorides at room temperature. It is also reportedly used in a novel route to be a safe reservoir for S=CF2 as a fluorinated surrogate for Thiophosgene, which allows large-scale and late-stage synthetic applications without special reaction control.
Efficient Synthesis of Trifluoromethyl Amines through a Formal Umpolung Strategy from the Bench-Stable Precursor (Me4N)SCF3.
Direct Synthesis of Acyl Fluorides from Carboxylic Acids with the Bench-Stable Solid Reagent (Me4N)SCF3.
Investigation of (Me4N)SCF3 as a Stable, Solid and Safe Reservoir for S=CF2 as a Surrogate for Thiophosgene.