2-Amino-6-chloropyridine-3-carboxylic acid

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem SID
Reaxys RN
2-Amino-6-chloronicotinic acid
Non-Fluorochemicals
KUMI0F26
58584-92-2
MFCD11045328
329767569
473763
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Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
2-Amino-6-chloropyridine-3-carboxylic acid
C6H5ClN2O2
172.57
≥98.0%
White to Faint Brown Liquid
224-230 °C
1g,5g,10g,25g,50g and 100g
Store at room temperature
2-Amino-6-chloropyridine-3-carboxylic acid is a useful synthetic building block to prepare biologically active molecules, e.g. synthesis of thiamine antagonist transketolase inhibitors and preparation of 2-aminonicotinic acid 1-oxides as inhibitors of quinolinic acid synthesis in the mammalian brain.
Synthesis, in vitro and in vivo activity of thiamine antagonist transketolase inhibitors. [1]
2-Aminonicotinic acid 1-oxides are chemically stable inhibitors of quinolinic acid synthesis in the mammalian brain: A step toward new antiexcitotoxic agents. [2]
References:
[1] A.A.Thomas, et al, Bioorg. Med. Chem. Lett., 2008, 18(6), pp 2206-2210.
[2] G.P.Vallerin, et al, J. Med. Chem., 2013, 56(23), pp 9482-9495.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319,H335
P261,P305+P351+P338

NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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