O-(2-(vinyloxy)ethyl)hydroxylamine

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
1-[2-(aminooxy)ethoxy]ethylene
Non-Fluorochemicals
KUMI0F31
391212-29-6
MFCD09951926
21867017
10334317
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Boiling Point
Packaging
Storage
O-(2-(vinyloxy)ethyl)hydroxylamine
C4H9NO2
103.12
≥98.0%
Yellow Liquid

1g,5g,10g,25g,50g and 100g
Store at 2-8 °C temperature
O-(2-(vinyloxy)ethyl)hydroxylamine is a pharmaceutially important intermediate for synthesis of various heterocyclic compounds as mitogen-activated protein kinase MEK inhibitors.
Potent and selective mitogen-activated protein kinase kinase(MEK)1,2 inhibitors. 1.4-(4-bromo-2-fluorophenylamino)-1-methylpyridin-2(1H)-ones. [1]
Structure-based design and synthesis of pyrrole derivatives as MEK inhibitors. [2]
Discovery of novel allosteric mitogen-activated protein kinase kinase (MEK) 1,2 inhibitors possessing bidentate Ser212 interactions. [3]
Structure based design of novel 6,5 heterobicyclic mitogen-activated protein kinase kinase (MEK) inhibitors leading to the discovery of imidazo[1,5-a] pyrazine G-479. [4]
References:
[1] E.M.Wallace, et al, J. Med. Chem., 2006, 49(2), pp 441-444.
[2] M.B.Wallace, et al, Bioorg. Med. Chem., 2010, 20(14), pp 4156-4158.
[3] R.A.Heald, et al, J. Med. Chem., 2012, 55(10), pp 4594-4604.
[4] K.D.Robarge,, et al, Bioorg. Med. Chem., 2014, 24(19), pp 4714-4723.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Not a dangerous goods



NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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