Tert-butyl 3-oxoazetidine-1-carboxylate is a useful building block for the synthesis of various pharmaceutical compounds, e.g. Antibacterial aminoglycoside analogs and Azetidinyl diamides as monoacylglycerol lipase inhibitors, etc..
The synthesis of 3-aryl-3-azetidinyl acetic acid esters by rhodium(I)-catalysed conjugate addition of organoboron reagents.
Synthesis of tert-butyl 6-oxo-2-azaspiro[3.3]heptane-2-carboxylate. 
Synthesis and Structural Analysis of a New Class of Azaspiro[3.3]heptanes as Building Blocks for Medicinal Chemistry.
Synthesis of novel azaspiro[3.4]octanes as multifunctional modules in drug discovery.
Synthesis of enantiopure dehydropiperidinones from α-amino acids and alkynes via azetidin-3-ones.