(3-Oxocyclobutyl)carbamic Acid tert-Butyl Ester

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
3-(Boc-amino)-1-cyclobutanone,Tert-butyl N-(3-oxocyclobutyl)carbamate
Non-Fluorochemicals
KUMI0F47
154748-49-9
MFCD09751872
23374584
13767464
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
(3-Oxocyclobutyl)carbamic Acid tert-Butyl Ester
C9H15NO3
185.22
≥98%(GC)
White to Beige Solid
120-125°C
5g,10g,20g,50g,100g and 500g
Store at room temperature
Tert-butyl N-(3-oxocyclobutyl)carbamate is a useful building block for the synthesis of various pharmaceutical compounds, e.g. 5-HT1-like receptor agonists and highly potent HCV NS4B inhibitors, etc..
Biotransformation of a novel positive allosteric modulator of metabotropic glutamate receptor subtype 5 contributes to seizure-like adverse events in rats involving a receptor agonism-dependent mechanism. [1]
Boc-protected 1-(3-oxocycloalkyl)ureas via a one-step Curtius rearrangement: Mechanism and scope. [2]
Highly Potent HCV NS4B Inhibitors with Activity against Multiple Genotypes. [3]
References:
[1] T.M.Bridges, et al, Drug Metab. Dispos, 2013, 41(9), pp 1703-1714.
[2] X.Sun, et al, Tetrahedron Lett., 2014, 55(4), pp 842-844.
[3] B.Phillips, et al, J. Med. Chem., 2014, 57(5), pp 2161-216.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Not a dangerous goods


2924297099
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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