1,4,7,10-Tetrazacyclododecane

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
Cyclen
Nonfluorochemicals
KUMI0F332
294-90-6
MFCD00066281
64963
606114
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
1,4,7,10-Tetrazacyclododecane
C8H20N4
172.28
≥98%
White to Off-White Solid
110-113°C
5g,10g,20g,50g,100g,500g and 1kg
Store at 2-8 temp.
1,4,7,10-Tetrazacyclododecane (aka Cyclen) is commonly used as catalyst in the cyclen-catalyzed Henry reaction of aldehydes with nitroalkanes under mild and neutral conditions. It is also employed in the preparation of Gadobutrol as a gadolinium-based magnetic resonance imaging (MRI) contrast agent (GBCA).
Cyclen-catalyzed Henry reaction under neutral conditions. [1] 
Reference:
[1] C.V.Le Bray, et al, Tetrahedro Lett., 2010, 51(34), pp 4555-4557.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Danger
H302,H312,H314,H410
P273,P280,P305+P351+P338,P310,P501
2933998049
UN 3259 8/PG II

1. Product Specification
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2. Safety Data Sheet
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