1-Amidinopyrazole hydrochloride

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
1H-Pyrazole-1-carboxamidine hydrochloride, Praxadine, HPCA
Non-Fluorochemicals, API & Intermediates, Guanidinylation Reagents
KUMI0F985
4023-02-3

PubChem ID

Reax
MFCD00210087

PubChem ID
2734672
5448758
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
1-Amidinopyrazole hydrochloride
C4H7ClN4
146.58
≥98%
White to Yellow Solid
167-170°C
10g,25g,50g,100g,250g,500g,1kg and 25kg
Store at room temperature
1-Amidinopyrazole hydrochloride (also known as 1H-Pyrazole-1-carboxamidine hydrochloride, Praxadine, HPCA, Zanamivir impurity F) is a heterocyclic compound typically used as guanidinylation reagent in the following applications: preparation of guanidylated hollow fiber membranes, • guanylation of amines and in peptide synthesis, synthesis of bis-guanidinium-cholesterol derivatives, etc.
1H-Pyrazole-1-carboxamidine hydrochloride an attractive reagent for guanylation of amines and its application to peptide synthesis. [1]
Effect of Surface Functionalization of MCM-41-Type Mesoporous Silica Nanoparticles on the Endocytosis by Human Cancer Cells. [2]
Guanidylated hollow fiber membranes based on brominated poly (2,6-dimethyl-1,4-phenylene oxide) (BPPO) for gold sorption from acid solutions. [3]
References:
[1] M.S.Bernatowicz, et al, J. Org. Chem., 1992, 57(8), pp 2497-2502.
[2] I.Slowing, et al, J. Am. Chem. Soc., 2006, 128(46), pp 14792-14793.
[3] J.Ran, et al, J. Hazard Mater., 2012, 241-242, pp 63-72.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H302,H317,H318,H335,H373,H412
P273,P260,P264,P280,P314,P305+P351+P338+P310
29331990
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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