(1S,2S)-(+)-N,N'-Dimethylcyclohexane-1,2-diamine (also named as (1S,2S)-(+)-1,2-Bis(methylamino)cyclohexane) is typically used in the preparation of PF-07059013, a noncovalent modulator of hemoglobin for treatment of sickle cell disease.
Synthesis of PI3K inhibitor GDC-0077 via a stereocontrolled N-arylation of α-amino acids.
PF-07059013: A Noncovalent Modulator of Hemoglobin for Treatment of Sickle Cell Disease. 
 C.Han, et al, Tetrahedron, 2019, 75(32), pp 4359-4357.
 A.Gopalsamy, et al, J. Med. Chem., 2021, 64(1), pp 326-342.