2-(4,6-Dimethyl-pyrimidin-2-yl)-octahydro-pyrrolo[3,4-c]pyrrole

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
 
Non-Fluorochemicals, API & Intermediates
KUMI0F981
1293284-71-5

PubChem ID

Reax
 

PubChem ID
 
21409450
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
2-(4,6-Dimethyl-pyrimidin-2-yl)-octahydro-pyrrolo[3,4-c]pyrrole
C12H18N4
218.30
≥98%
White to Yellow Solid

5g,10g,25g,50g,100g,250g,500g,1kg and 25kg
Store at room temperature
2-(4,6-Dimethyl-pyrimidin-2-yl)-octahydro-pyrrolo[3,4-c]pyrrole is a heterocycle intermediate typically used in the preparation of Seltorexant (former developmental code names MIN-202, JNJ-42847922, JNJ-922) is a selective, small-molecule antagonist of the OX2 receptor for the treatment of insomnia and major depressive disorder (MDD).
Small-molecule antagonists of the orexin receptors. [1]
Discovery and development of orexin receptor antagonists as therapeutics for insomnia. [2]
References:
[1] J.A.Christoper, et al, Pharm. Pat. Anal., 2014, 3(6), pp 625-638.
[2] C.J.Winrow, et al, Br. J. Pharmacol., 2014, 171(2), pp 283-293.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Not regulated
 
 
29339980
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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