2,4,6-Trimethylaniline

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
2,4,6-TMA, Mesidine
Non-Fluorochemicals, API & Intermediates
KUMI0F1010
88-05-1

PubChem ID

Reax
MFCD00007740

PubChem ID
6931
636559
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Boiling Point
Packaging
Storage
2,4,6-Trimethylaniline
C9H13N
135.21
≥98%
Colorless to Yellow Clear Liquid
230-233°C
5g,10g,25g,50g,100g,250g,500g,1kg and 25kg
Store at room temperature
2,4,6-Trimethylaniline (also known as 2,4,6-TMA, Mesidine)is typically used in the synthesis of Grubbs' catalyst, dyes and pharmaceutically active substances. For example, it is the starting material for the prepartion of Dapivirine, a non-nucleoside reverse transcriptase inhibitor to prevent infection by human immunodeficiency virus in women.
Mechanisms of inhibition of HIV replication by nonnucleoside reverse transcriptase inhibitors. [1]
Selective Halogenation Using an Aniline Catalyst. [2]
1,3-Bis(2,4,6-trimethylphenyl)triazenides of potassium, magnesium, calcium, and strontium. [3]
References:
[1] N.Sluis-Cremer, et al, Virus Res., 2008, 134(1-2), pp 147-156.
[2] R.C.Samanta, et al, Chem. Eur. J., 2015, 21(34), pp 11976-11979.
[3] D.Kalden, et al, Dalton Trans., 2015, 44(17), pp 8089-8099.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Danger
H302+H312,H315,H319,H330
P280,P301+P312+P330,P302+P352+P312,P304+P340+P310,P305+P351+P338
29214900
UN 2810 6.1/PG II

1. Product Specification
2. Safety Data Sheet
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