2-(4-Aminophenyl)-2-methylpropionitrileis a cyclic cyanide containing aminophenyl group that typically used as pharmaceutical intermediate in the preparation of Dactolisib (RTB-101,Previousy BEZ235), which is an imidazoquinoline derivative acting as a PI3K/mTOR inhibitor.
The Efficacy of a Novel, Dual PI3K/mTOR Inhibitor NVP-BEZ235 to Enhance Chemotherapy and Antiangiogenic Response in Pancreatic Cancer. 
Synthesis and biological activity of imidazo[4,5-c]quinoline derivatives as PI3K/mTOR inhibitors. 
 N.Awasthi, et al, J. Cell. Biochem., 2012, 113(3), pp 784-791.
 Y.Li, et al, Chem. Res. Chinese U., 2017, 33(6), pp 895-902.
UN 2811 6.1 / PGIII
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