2-(4-Aminophenyl)-2-methylpropionitrile

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
1,1-Dimethyl-1-(4-aminophenyl)-acetonitrile
Nonfluorochemicals, API&Intermediates
KUMI0F235
115279-57-7
MFCD09909912
10057801
2964107
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
2-(4-Aminophenyl)-2-methylpropionitrile
C10H12N2
160.22
≥98%
Yellow to Orange Solid
40-45°C
5g,10g,20g,50g,100g,500g and 1kg
Store at room temperature
2-(4-Aminophenyl)-2-methylpropionitrile is a cyclic cyanide containing aminophenyl group that typically used as pharmaceutical intermediate in the preparation of Dactolisib (RTB-101,Previousy BEZ235), which is an imidazoquinoline derivative acting as a PI3K/mTOR inhibitor.
The Efficacy of a Novel, Dual PI3K/mTOR Inhibitor NVP-BEZ235 to Enhance Chemotherapy and Antiangiogenic Response in Pancreatic Cancer. [1]
Synthesis and biological activity of imidazo[4,5-c]quinoline derivatives as PI3K/mTOR inhibitors. [2]
References:
[1] N.Awasthi, et al, J. Cell. Biochem., 2012, 113(3), pp 784-791.
[2] Y.Li, et al, Chem. Res. Chinese U., 2017, 33(6), pp 895-902.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Danger
H302,H315,H319,H335
P264,P302+P352,P304+P340,P305+P351+P335
2926909090
UN 2811 6.1 / PGIII

1. Product Specification
2. Safety Data Sheet
Please inquire for pricing and availability of this product by writing email to sales@kumidas.com.