2-Amino-5-bromo-3-methylpyridine

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
2-Amino-5-bromo-3-picoline, 2-Amino-3-methyl-5-bromopyridine
Non-Fluorochemicals, API & Intermediates
KUMI0F971
3430-21-5

PubChem ID

Reax
MFCD00068232

PubChem ID
137934
386426
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Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
2-Amino-5-bromo-3-methylpyridine
C6H7BrN2
187.04
≥98%
Light Yellow  to Brown Solid
88-95°C
5g,10g,25g,50g,100g,250g,500g,1kg and 25kg
Store at room temperature
2-Amino-5-bromo-3-methylpyridine is a heterocycle intermediate used in the preparation of various compounds in organic synthesis, e.g. a selective autotaxin inhibitor of Ziritaxestat (GLPG-1690).
Synthesis of the grass alkaloid perlolidine through a pyridyne cyclisation reaction. [1]
Microwave-Assisted One-Pot Synthesis of Substituted 3-Bromoimidazo [1, 2-a] pyridines and Imidazoheterocycles. [2]
Catalyst-Free Cyclization- And Curtius Rearrangement-Induced Functional Group Transformation: An Improved Synthetic Strategy of First-in-Class ATX Inhibitor Ziritaxestat (GLPG-1690). [3]
References:
[1] S.V.Kessar, et al, Indian J. Chem., 2001, 40B(11), pp 1129-1131.
[2] S.M.Patil, et al, J. Heterocycl. Chem., 2014, 51(5), pp 1509-1515.
[3] H.Lei, et al, Org. Process Res. Dev., 2020, 24(6), pp 997-1005.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319,H335
P302+P352,P305+P351+P338
29333999
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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