2-Amino-5-bromopyridine

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
5-Bromo-2-pyridylamine
Nonfluorochemicals, API&Intermediates
KUMI0F294
1072-97-5
MFCD00006323

Rea
70622

Reax
108737
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Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
2-Amino-5-bromopyridine
C5H5BrN2
173.01
98%
White to Brown Solid
133-138°C
5g,10g,25g,50g,100g,250g,500g,1kg and 25kg
Store at room temperture
2-Amino-5-bromopyridine is a heterocyclic intermediate that commonly used in organic synthesis. One recent example is employed in the preparation of RG7916 as a selective survival of Motor Neuron-2 (SMN2) Gene Splicing Modifier for the treatment of spinal muscular atrophy (SMA).
Risdiplam distributes and increases SMN protein in both the central nervous system and peripheral organs. [1]
Discovery of Risdiplam, a Selective Survival of Motor Neuron-2 (SMN2) Gene Splicing Modifier for the Treatment of Spinal Muscular Atrophy (SMA). [2]
References:
[1] A.Poirier, et al, Pharmacol. Res. Perspect, 2018, 6(6):e00447.
[2] H.Ratni, et al, J. Med. Chem., 2019, 61(15), pp 6501-6517.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319,H335
P305+P351+P338
2933399990
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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