2-Bromo-1-cyclopropylethanone

Synonym

Product Category

Product Code

CAS Number

MDL Number

Pubchem CID

Reaxys RN

1-Bromomethyl cyclopropyl ketone

Nonfluorochemicals, API&Intermediates

KUMI0F245

69267-75-0

MFCD08460238

10920841

2429402

image-155171-Trimethyl(trifluoromethyl)silane_reagent.png

Specification
Applications
Safety & Regulations
Product Documents

Chemical Name

Molecular Formula

Molecular Weight

Assay

Appearance

Melting Point

Packaging

Storage

2-Bromo-1-cyclopropylethanone

C5H7BrO

163.01

≥98%

White to Pale Yellow Solid

5g,10g,20g,50g,100g,500g and 1kg

Store at room temperature

2-Bromo-1-cyclopropylethanone is an intermediate commonly used in the prepartion of some pharmaceutically active substances, such as potent and selective human A3 adenosine receptor antagonists and apoptosis sigsomenal-regulating kinase 1 (ASK1) inhibitors.

New Pyrrolo[2,1-f]purine-2,4-dione and Imidazo[2,1-f]purine-2,4-dione Derivatives as Potent and Selective Human A3 Adenosine Receptor Antagonists. [1]

Selonsertib (GS-4997), an ASK1 inhibitor, antagonizes multidrug resistance in ABCB1- and ABCG2-overexpressing cancer cells. [2]

References:

[1] P.G.Baraldi, et al, J. Med. Chem., 2005, 48(14), pp 4697-4701.

[2] N.Ji, et al, Cancer Lett., 2019, 440-441, pp 82-93.

Signal Word

Hazard Statements

Precautionary Statements

HS Code

RIDADR

Legal Information

Danger

H301,H319

P301+P310,P305+P351+P338

2914790090

UN 2811 6.1/PG III

1. Product Specification

2. Safety Data Sheet

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