2-Chloro-1-(3-hydroxyazetidin-1-yl)ethan-1-one

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
2-Chloranyl-1-(3-oxidanylazetidin-1-yl)ethanone
Non-Fluorochemicals, API & Intermediates
KUMI0F972
1628263-61-5

PubChem ID

Reax
MFCD29988233

PubChem ID
90446601
 
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Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
2-Chloro-1-(3-hydroxyazetidin-1-yl)ethan-1-one
C5H8ClNO2
149.58
≥98%
Light Yellow  to Yellow Solid
 
5g,10g,25g,50g,100g,250g,500g,1kg and 25kg
Store at room temperature
2-Chloro-1-(3-hydroxyazetidin-1-yl)ethan-1-one is a heterocycle intermediate typically used in the preparation of Ziritaxestat (GLPG-1690), a selective autotaxin inhibitor for the treatment of patients with idiopathic pulmonary fibrosis (IPF) or chronic obstructive pulmonary diseases (COPD).
Catalyst-Free Cyclization- And Curtius Rearrangement-Induced Functional Group Transformation: An Improved Synthetic Strategy of First-in-Class ATX Inhibitor Ziritaxestat (GLPG-1690). [1]
Reference:
[1] H.Lei, et al, Org. Process Res. Dev., 2020, 24(6), pp 997-1005.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H302,H315,H319,H335
P261,P280,P301+P312,P302+P352,P305+P351+P338
29339980
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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