2-Methoxy-3-(1-methyl-1,2,4-triazol-3-yl)aniline

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
2-Methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)aniline
Non-Fluorochemicals, API & Intermediates
KUMI0F1014
1609394-10-6

PubChem ID

Reax
MFCD30489435

PubChem ID
90135673
26837594
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
2-Methoxy-3-(1-methyl-1,2,4-triazol-3-yl)aniline
C10H12N4O
204.23
≥98%
White to Yellow Solid
 
5g,10g,25g,50g,100g,250g,500g,1kg and 25kg
Store at room temperature
2-Methoxy-3-(1-methyl-1,2,4-triazol-3-yl)aniline is an intermediate typically used in the preparation of BMS-986165, a highly potent and selective allosteric inhibitor of TYK2.
Phase 2 Trial of Selective Tyrosine Kinase 2 Inhibition in Psoriasis. [1]
Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165. [2]
References:
[1] K.Papp, et al, N. Engl. J. Med., 2018, 379(14), pp 1313-1321.
[2] S.T.Wrobleski, et al, J. Med. Chem., 2019, 62(20), pp 8973-8995.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319,H335
P302+P312,P305+P351+P338
29339980
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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