(2S)-2-aminobutanamide hydrochloride

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
H-ABU-NH2 HCl, S-ABA HCl
Non-Fluorochemicals, API & Intermediates
KUMI0F978
7682-20-4

PubChem ID

Reax
MFCD00136565

PubChem ID
11961924
 
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
(2S)-2-aminobutanamide hydrochloride
C4H11ClN2O
138.59
≥98%
White to Off-white Solid
259-263°C
10g,25g,50g,100g,250g,500g,1kg and 25kg
Store at room temperature
(2S)-2-aminobutanamide hydrochloride (also known as H-ABU-NH2 HCl, S-ABA HCl) is primarily used in the preparation of Brivaracetam (UCB 34714 ) for the treatment of partial-onset seizures with or without secondary generalisation, in combination with other antiepileptic drugs.
Anti-convulsive and anti-epileptic properties of brivaracetam (ucb 34714), a high-affinity ligand for the synaptic vesicle protein, SV2A. [1]
The pharmacokinetics, CNS pharmacodynamics and adverse event profile of brivaracetam after multiple increasing oral doses in healthy men. [2]
References:
[1] A.Matagne, et al, Br. J. Pharmcol., 2008, 154(8), pp 1662-1671.
[2] P.Rolan, et al, Br. J. Pharmcol, 2008, 66(1), pp 71-75.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319,H335
P305+P352,P305+P351+P338
29241900
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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