4-Amino-3-bromo-5-nitropyridine

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
3-Bromo-5-nitropyridin-4-amine
Nonfluorochemicals, API&Intermediates
KUMI0F265
89284-05-9
MFCD01646057

Rea
4997588

Reax
147658
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
4-Amino-3-bromo-5-nitropyridine
C5H4BrN3O2
218.01
98%
Yellow to Orange Solid
174-175°C
5g,10g,25g,50g,100g,250g,500g,1kg and 25kg
Store at room temperture
4-Amino-3-bromo-5-nitropyridine is a pharmaceutial intermediate that typically in the preparation of SM-04690, a small-molecule inhibitor of the Wnt pathway which is being investigated as a potential disease modifying agent for the treatment of osteoarthritis of the knee.
A novel Wnt pathway inhibitor, SM04690, for the treatment of moderate to severe osteoarthritis of the knee: results of a 24-week, randomized, controlled, phase 1 study. [1]
A small-molecule inhibitor of the Wnt pathway (SM04690) as a potential disease modifying agent for the treatment of osteoarthritis of the knee. [2]
References:
[1] Y.Yazici, et al, Osteoarthritis Cartilage, 2017, 25(10), pp 1598-1606.
[2] V.Deshmukh, et al, Osteoarthritis Cartilage, 2018, 26(1), pp 18-27.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H302,H315,H319,H335
P261,P280,P305+P351+P338
2933399990
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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