Cyclopropanecarboxamide

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
Carbamoylcyclopropane, Cyclopropylamino acid
Non-Fluorochemicals, API & Intermediates
KUMI0F1012
6228-73-5

PubChem ID

Reax
MFCD00013729

PubChem ID
80376
1924346
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
Cyclopropanecarboxamide
C4H7NO
85.11
≥98%
White to Yellow Solid
121-126°C
5g,10g,25g,50g,100g,250g,500g,1kg and 25kg
Store at room temperature
Cyclopropanecarboxamide (also known as Carbamoylcyclopropane, Cyclopropylamino acid) is an intermediate typically used in the preparation of BMS-986165, a highly potent and selective allosteric inhibitor of TYK2.
Lithium Chloride-Mediated Stereoselective Synthesis of Cyclopropanecarboxamides from gamma,delta-Epoxy Malonates through a Domino Cyclopropanation/Lactonization/ Aminolysis Process. [1]
Synthesis of Oxazolines from Amides via Palladium-Catalyzed Functionalization of Unactivated C(sp3)-H Bond. [2]
Phase 2 Trial of Selective Tyrosine Kinase 2 Inhibition in Psoriasis. [3]
References:
[1] M.V.Marques, et al, J. Org. Chem., 2014, 79(10), pp 4650-4658.
[2] B.Li, et al, Org. Lett., 2015, 17(5), pp 1200-1203.
[3] K.Papp, et al, N. Engl. J. Med., 2018, 379(14), pp 1313-1321.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Not regulated
 
 
292429000
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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