5-Cyclopropyl-1H-imidazole

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
5-Cyclopropyl imidazole
Nonfluorochemicals, API&Intermediates
KUMI0F247
89830-98-8
MFCD18711516
19031522
20731519
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
5-Cyclopropyl-1H-imidazole
C6H8N2
108.14
≥98%
White to Brown Solid

5g,10g,20g,50g,100g,500g and 1kg
Store at room temperature
5-Cyclopropyl-1H-imidazole is an intermediate commonly used in the prepartion of some pharmaceutically active substances, such as H3 histamine receptor ligands and apoptosis sigsomenal-regulating kinase 1 (ASK1) inhibitors.
Synthesis and biological evaluation of novel 2-(1H-imidazol-4-yl)cyclopropane carboxylic acids: Key intermediates for H3 histamine receptor ligands. [1]
Selonsertib (GS-4997), an ASK1 inhibitor, antagonizes multidrug resistance in ABCB1- and ABCG2-overexpressing cancer cells. [2]
References:
[1] M.F.Brana, et al, Bioorg. Med. Chem. Lett., 2002, 12(24), pp 3561-3563.
[2] N.Ji, et al, Cancer Lett., 2019, 440-441, pp 82-93.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H302,H315,H319,H335
P261,P305+P351+P338
2933399990
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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