6-(6-Chloropyridin-2-yl)-1,3,5-triazine-2,4(1H,3H)-dione is a heterocyclic intermediate that typically used in the preparation of AG-881 as a potent and selective orally available inhibitor of mutated forms of both isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) for patients with IDH mutation-positive hematologic malignancies and solid tumors.
The Evolving Landscape in the Development of Isocitrate Dehydrogenase Mutant Inhibitors. [1]
Reference:
[1] J.Chen, et al, Mini Rev. Med. Chem., 2016, 16(16), pp 1344-1358.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319
P264,P280,P305+P351+P338
2933399990
NONH for all modes of transport
1. Product Specification
2. Safety Data Sheet
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