6-Bromo-4-chloro-3-nitroquinoline

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
3-Nitro-4-chloro-6-bromoquinoline
Nonfluorochemicals, API&Intermediates
KUMI0F236
723281-72-9
MFCD09909913
10057801
21984128
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
6-Bromo-4-chloro-3-nitroquinoline
C9H4BrClN2O2
287.50
≥98%
White to Brown Solid
130-132°C
5g,10g,20g,50g,100g,500g and 1kg
Store at room temperature
6-Bromo-4-chloro-3-nitroquinoline is a quinoline-based derivative that commonly used as pharmaceutical intermediate in the preparation of various PI3K/mTOR inhibitors.
Novel quinoline-derived mTOR inhibitors with remarkable enzymatic and cellular activities: Design, synthesis and biological evaluation. [1]
Synthesis and biological activity of imidazo[4,5-c]quinoline derivatives as PI3K/mTOR inhibitors. [2]
Discovery of 1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-ones based novel, potent and PI3Kδ selective inhibitors. [3]
References:
[1] X.Ma, et al, MedChemComm, 2016, 7(2), pp 297-310.
[2] Y.Li, et al, Chem. Res. Chinese U., 2017, 33(6), pp 895-902.
[3] R.Bahekar, et al, Bioorg. Med. Chem., 2019, 19(11), pp 1313-1319.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319,H335
P302+P352,P337+P313,P304+P340,P305+P351+P335
2933499090
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
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