6-Chloro-7-deazapurine

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine
Nonfluorochemicals, API&Intermediates
KUMI0F237
3680-69-1
MFCD01686865
5356682
607871
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
6-Chloro-7-deazapurine
C6H4ClN3
153.57
≥98%
White to Beige Solid
188-194°C
5g,10g,20g,50g,100g,500g and 1kg
Store at room temperature
6-Chloro-7-deazapurine is commonly used as intermediate in the preparation of pharmaceutically active substances, such as Itacitinib (also named as INCB39110, INCB039110), which is a potent and selective inhibitor of JAK1 tyrosine kinase inhibitor in the treatment of rheumatoid arthritis, myelofibrosis, rheumatoid arthritis and plaque psoriasis.
A randomized, double-blind, placebo-controlled, dose-escalation study of the safety and efficacy of INCB039110, an oral janus kinase 1 inhibitor, in patients with stable, chronic plaque psoriasis. [1]
Reference:
[1] R.Bissonnette, et al, J. Dermatolog. Treat., 2016, 27(4), pp 332-338.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Danger
H301
P301+P310
2933599590
UN 2811 6.1/PG III

1. Product Specification
2. Safety Data Sheet
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