6-Methoxy-3-pyridinecarboxaldehyde

Synonym
Product Category
Product Code
CAS Number
MDL Number
Pubchem CID
Reaxys RN
6-Methoxy-3-nicotinaldehyde
Nonfluorochemicals, API&Intermediates
KUMI0F286
65873-72-5
MFCD02683446

Rea
3364576

Reax
1446751
image-155171-Trimethyl(trifluoromethyl)silane_reagent.png
Chemical Name
Molecular Formula
Molecular Weight
Assay
Appearance
Melting Point
Packaging
Storage
6-Methoxy-3-pyridinecarboxaldehyde
C7H7NO2
137.14
98%
White to Pale Yellow Solid
42-46°C
5g,10g,25g,50g,100g,250g,500g,1kg and 25kg
Store at room temperture
6-Methoxy-3-pyridinecarboxaldehyde is a heterocyclic intermediate that commonly used in organic synthesis. A recent example is empolyed to prepare LOXO-292 as a selective and potent RET kinase inhibitor for the treatment of RET fusion-positive and RET-mutant cancers alike.
Synthesis of 3,6-diazabicyclo[3.1.1]heptanes as novel ligands for neuronal nicotinic acetylcholine receptors. [1]
Design of novel 3,6-diazabicyclo[3.1.1]heptane derivatives with potent and selective affinities for α4β2 neuronal nicotinic acetylcholine receptors. [2]
Selective RET kinase inhibition for patients with RET-altered cancers. [3]
LOXO-292 Reins In RET-Driven Tumors. [4]
References:
[1] G.Murineddu, et al, Bioorg. Med. Chem. Lett., 2008, 18(23), pp 6147-6152.
[2] F.Deligia, et al, Eur. J. Med. Chem., 2015, 103, pp 429-437.
[3] V.Subbiah, et al, Ann. Oncol., 2018, 29(8), pp 1869-1876.
[4] No authors listed, Cancel Discov., 2018, 8(8), pp 904-905.
Signal Word
Hazard Statements
Precautionary Statements
HS Code
RIDADR
Legal Information
Warning
H315,H319,H335
P261,P305+P351+P338
2933399990
NONH for all modes of transport

1. Product Specification
2. Safety Data Sheet
Please inquire for pricing and availability of this product by writing email to sales@kumidas.com.